{"id":5979,"date":"2013-09-26T07:15:37","date_gmt":"2013-09-26T00:15:37","guid":{"rendered":"http:\/\/antoansinhhoc.vn\/?p=1015"},"modified":"2013-09-26T07:15:37","modified_gmt":"2013-09-26T00:15:37","slug":"nghien-cuu-thanh-cong-du-du-moi-khang-benh-nang-suat-cao","status":"publish","type":"post","link":"https:\/\/nbca.gov.vn\/nghien-cuu-thanh-cong-du-du-moi-khang-benh-nang-suat-cao\/","title":{"rendered":"Nghi\u00ean c\u1ee9u th\u00e0nh c\u00f4ng \u0111u \u0111\u1ee7 m\u1edbi kh\u00e1ng b\u1ec7nh, n\u0103ng su\u1ea5t cao"},"content":{"rendered":"
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Hi\u1ec7n nay, c\u00e1c c\u00e2y \u0111\u1ee7 \u0111\u1ee7 tr\u1ed3ng \u1edf Vi\u1ec7t Nam, c\u1ee9 6 th\u00e1ng sau khi tr\u1ed3ng l\u00e0 l\u1ea1i b\u1ecb b\u1ec7nh virus \u0111\u1ed1m v\u00f2ng, khi\u1ebfn c\u00e2y c\u00f2i c\u1ecdc, kh\u00f4ng ra \u0111\u01b0\u1ee3c nhi\u1ec1u qu\u1ea3. V\u00ec th\u1ebf, ng\u01b0\u1eddi tr\u1ed3ng c\u1ee9 sau 1 v\u1ee5 th\u01b0\u1eddng ph\u1ea3i ch\u1eb7t \u0111i tr\u1ed3ng l\u1ea1i c\u00e2y m\u1edbi. \u0110\u00f3 \u0111\u00f3, m\u1ea5t r\u1ea5t nhi\u1ec1u th\u1eddi gian, c\u00f4ng s\u1ee9c l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 kinh t\u1ebf.<\/p>\n<\/div>\n

C\u1ee9 tr\u1ed3ng \u0111u \u0111\u1ee7 6 th\u00e1ng l\u00e0 \u201cd\u00ednh\u201d b\u1ec7nh \u0111\u1ed1m v\u00f2ng<\/strong><\/p>\n<\/div>\n

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Hi\u1ec7n nay, c\u00e1c c\u00e2y \u0111\u1ee7 \u0111\u1ee7 tr\u1ed3ng \u1edf Vi\u1ec7t Nam, c\u1ee9 6 th\u00e1ng sau khi tr\u1ed3ng l\u00e0 l\u1ea1i b\u1ecb b\u1ec7nh virus \u0111\u1ed1m v\u00f2ng, khi\u1ebfn c\u00e2y c\u00f2i c\u1ecdc, kh\u00f4ng ra \u0111\u01b0\u1ee3c nhi\u1ec1u qu\u1ea3. V\u00ec th\u1ebf, ng\u01b0\u1eddi tr\u1ed3ng c\u1ee9 sau 1 v\u1ee5 th\u01b0\u1eddng ph\u1ea3i ch\u1eb7t \u0111i tr\u1ed3ng l\u1ea1i c\u00e2y m\u1edbi. \u0110\u00f3 \u0111\u00f3, m\u1ea5t r\u1ea5t nhi\u1ec1u th\u1eddi gian, c\u00f4ng s\u1ee9c l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 kinh t\u1ebf.<\/p>\n

C\u00e1c n\u01b0\u1edbc kh\u00e1c tr\u00ean th\u1ebf gi\u1edbi c\u0169ng c\u00f3 t\u00ecnh tr\u1ea1ng t\u01b0\u01a1ng t\u1ef1. Nh\u01b0ng b\u1eb1ng c\u00f4ng ngh\u1ec7 chuy\u1ec3n gen, h\u1ecd \u0111\u00e3 t\u1ea1o ra c\u00e1c lo\u1ea1i gi\u1ed1ng kh\u00e1ng \u0111\u01b0\u1ee3c b\u1ec7nh, c\u00f3 th\u1ec3 thu ho\u1ea1ch qu\u1ea3 li\u00ean t\u1ee5c nhi\u1ec1u n\u0103m m\u00e0 ch\u1ec9 ph\u1ea3i tr\u1ed3ng 1 l\u1ea7n.<\/p>\n

Tuy v\u1eady, nh\u1eefng gi\u1ed1ng c\u1ee7a n\u01b0\u1edbc ngo\u00e0i l\u1ea1i ch\u01b0a th\u1ef1c s\u1ef1 ph\u00f9 h\u1ee3p v\u1edbi Vi\u1ec7t\u00a0<\/span>Nam \u00a0v\u00e0 kh\u00f4ng kh\u00e1ng \u0111\u01b0\u1ee3c c\u00e1c d\u00f2ng virus g\u00e2y b\u1ec7nh hay g\u1eb7p \u1edf Vi\u1ec7t\u00a0<\/span>Nam.<\/p>\n

V\u00ec th\u1ebf, y\u00eau c\u1ea7u ph\u1ea3i t\u1ea1o ra \u0111\u01b0\u1ee3c c\u00e1c gi\u1ed1ng \u0111u \u0111\u1ee7 ch\u1ed1ng l\u1ea1i \u0111\u01b0\u1ee3c c\u00e1c d\u00f2ng virus g\u00e2y b\u1ec7nh \u0111\u1ed1m v\u00f2ng hay g\u1eb7p c\u1ee7a Vi\u1ec7t\u00a0<\/span>Nam, cho ra nhi\u1ec1u qu\u1ea3 c\u00f3 ch\u1ea5t l\u01b0\u1ee3ng t\u1ed1t\u2026\u0111\u00e3 \u0111\u1eb7t ra cho nh\u1eefng ng\u01b0\u1eddi l\u00e0m nghi\u00ean c\u1ee9u.<\/p>\n

Th\u00e0nh c\u00f4ng c\u1ee7a c\u00e1c nh\u00e0 khoa h\u1ecdc Vi\u1ec7t<\/strong><\/p>\n

PGS TS Chu Ho\u00e0ng H\u00e0, Ph\u00f3 Vi\u1ec7n tr\u01b0\u1edfng vi\u1ec7n C\u00f4ng ngh\u1ec7 sinh h\u1ecdc, vi\u1ec7n H\u00e0n l\u00e2m KHCN Vi\u1ec7t Nam \u0111\u00e3 ch\u1ee7 tr\u00ec \u0111\u1ec1 t\u00e0i \u201cNghi\u00ean c\u1ee9u t\u1ea1o gi\u1ed1ng c\u00e2y \u0103n qu\u1ea3 kh\u00e1ng b\u1ec7nh virus ph\u1ed5 r\u1ed9ng b\u1eb1ng k\u1ef9 thu\u1eadt chuy\u1ec3n gen \u0111a \u0111o\u1ea1n\u201d thu\u1ed9c Ch\u01b0\u01a1ng tr\u00ecnh KHCN c\u1ea5p nh\u00e0 n\u01b0\u1edbc (KC.04\/06-10).<\/p>\n

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C\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 t\u1eadn d\u1ee5ng m\u1ed9t c\u01a1 ch\u1ebf r\u1ea5t \u0111\u1eb7c bi\u1ec7t c\u1ee7a t\u1ebf b\u00e0o th\u1ef1c v\u1eadt. \u0110\u00f3 l\u00e0 kh\u1ea3 n\u0103ng \u0111i\u1ec1u khi\u1ec3n gen sau phi\u00ean m\u00e3. Nhi\u1ec1u lo\u1ea1i virus g\u00e2y b\u1ec7nh \u0111\u00e3 c\u00f3 th\u1ec3 ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c th\u00f4ng qua bi\u1ec7n ph\u00e1p t\u1ea1o c\u00e2y tr\u1ed3ng chuy\u1ec3n gen mang c\u00e1c gen ho\u1eb7c \u0111o\u1ea1n gen c\u00f3 ngu\u1ed3n g\u1ed1c t\u1eeb ch\u00ednh c\u00e1c virus g\u00e2y b\u1ec7nh (pathogen-derived resistance, PDR). C\u00e1c c\u1ea5u tr\u00fac gen c\u00f3 ngu\u1ed3n g\u1ed1c t\u1eeb virus g\u00e2y b\u1ec7nh \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng chuy\u1ec3n v\u00e0o c\u00e2y tr\u1ed3ng \u0111\u1ec3 t\u1ea1o t\u00ednh kh\u00e1ng c\u00f3 th\u1ec3 l\u00e0 c\u00e1c lo\u1ea1i kh\u00e1c nhau nh\u01b0: c\u00e1c c\u1ea5u tr\u00fac c\u1ee7a virus theo chi\u1ec1u xu\u00f4i (sense) hay chi\u1ec1u ng\u01b0\u1ee3c (antisense), c\u00e1c c\u1ea5u tr\u00fac d\u1ea1ng k\u1eb9p t\u00f3c (inverted repeats\/hairpin) v\u00e0 c\u00e1c miRNA nh\u00e2n t\u1ea1o c\u00f3 \u0111\u00edch l\u00e0 c\u00e1c tr\u00ecnh t\u1ef1 gen c\u1ee7a virus g\u00e2y b\u1ec7nh, hay k\u1ef9 thu\u1eadt RNAi \u201cRNA interference\u201d, \u0111ang \u0111\u01b0\u1ee3c quan t\u00e2m nhi\u1ec1u v\u00e0 \u1ee9ng d\u1ee5ng r\u1ed9ng r\u00e3i. Th\u00f4ng qua c\u01a1 ch\u1ebf n\u00e0y c\u00f3 th\u1ec3 t\u1ea1o ra cho c\u00e2y tr\u1ed3ng kh\u1ea3 n\u0103ng \u0111\u1ec1 kh\u00e1ng v\u1edbi c\u00e1c ARN c\u1ee7a virus, n\u1ebfu ARN virus x\u00e2m nh\u1eadp v\u00e0o t\u1ebf b\u00e0o th\u1ef1c v\u1eadt s\u1ebd l\u1eadp t\u1ee9c b\u1ecb ph\u00e1 h\u1ee7y, kh\u00f4ng h\u00ecnh th\u00e0nh \u0111\u01b0\u1ee3c c\u1ea5u tr\u00fac h\u1ea1t \u0111\u1eb7c tr\u01b0ng c\u1ee7a n\u00f3 …<\/div>\n<\/div>\n

Trong khu\u00f4n kh\u1ed5 nghi\u00ean c\u1ee9u c\u1ee7a \u0111\u1ec1 t\u00e0i, PGS TS Chu Ho\u00e0ng H\u00e0 v\u00e0 \u0111\u1ed3ng nghi\u1ec7p \u0111\u00e3 x\u00e2y d\u1ef1ng \u0111\u01b0\u1ee3c m\u1ed9t quy tr\u00ecnh ho\u00e0n ch\u1ec9nh \u0111\u1ec3 t\u1ea1o ra c\u00e1c c\u00e2y \u0111u \u0111\u1ee7 chuy\u1ec3n gen. Trong quy tr\u00ecnh n\u00e0y c\u00e1c h\u1ea1t \u0111u \u0111\u1ee7 non \u0111\u01b0\u1ee3c l\u1ef1a ch\u1ecdn, t\u00e1ch l\u1ea5y ph\u00f4i \u0111\u1ec3 nu\u00f4i c\u1ea5y t\u1ea1o m\u00f4 s\u1eb9o v\u00e0 g\u00e2y nhi\u1ec5m vi khu\u1ea9n \u0111\u1ec3 chuy\u1ec3n gen, ch\u1ecdn l\u1ecdc v\u00e0 t\u00e1i sinh c\u00e2y ho\u00e0n ch\u1ec9nh. Sau \u0111\u00f3, c\u00e1c d\u00f2ng \u0111u \u0111\u1ee7 s\u1ebd \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 t\u00ednh kh\u00e1ng b\u1ec7nh th\u00f4ng qua l\u00e2y nhi\u1ec5m nh\u00e2n t\u1ea1o, ch\u1ecdn l\u1ecdc qua c\u00e1c th\u1ebf h\u1ec7 \u0111\u1ec3 l\u1ef1a ch\u1ecdn \u0111\u01b0\u1ee3c c\u00e1c d\u00f2ng c\u00e2y v\u1eeba kh\u00e1ng b\u1ec7nh t\u1ed1t v\u1eeba cho n\u0103ng su\u1ea5t cao \u0111\u1ec3 \u0111\u01b0a v\u00e0o s\u1ea3n xu\u1ea5t.<\/p>\n

Trong su\u1ed1t qu\u00e1 tr\u00ecnh k\u00e9o d\u00e0i h\u01a1n 4 n\u0103m tr\u1eddi n\u00e0y, PGS TS Chu Ho\u00e0ng H\u00e0 v\u00e0 nh\u00f3m nghi\u00ean c\u1ee9u v\u1edbi nhi\u1ec1u c\u00e1n b\u1ed9 tr\u1ebb \u0111\u00e3 ph\u1ea3i \u0111i h\u01a1n 30 t\u1ec9nh, v\u1edbi nhi\u1ec1u v\u00f9ng \u0111\u1ecba l\u00fd t\u01b0\u01a1ng \u0111\u1ed1i c\u00e1ch bi\u1ec7t, \u0111\u1ec3 l\u1ea5y m\u1eabu c\u00e1c lo\u1ea1i \u0111u \u0111\u1ee7 v\u00e0 c\u00e1c m\u1eabu virus g\u00e2y b\u1ec7nh kh\u00e1c nhau \u0111\u1ec3 ph\u1ee5c cho cho nghi\u00ean c\u1ee9u. Th\u00f4ng qua vi\u1ec7c ph\u00e2n l\u1eadp v\u00e0 x\u00e1c \u0111\u1ecbnh tr\u00ecnh t\u1ef1 gen c\u1ee7a c\u00e1c virus g\u00e2y b\u1ec7nh, c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 \u0111\u00e1nh gi\u00e1 \u0111\u01b0\u1ee3c m\u1ee9c \u0111\u1ed9 \u0111a d\u1ea1ng di truy\u1ec1n c\u1ee7a qu\u1ea7n th\u1ec3 virus g\u00e2y b\u1ec7nh v\u00e0 l\u1ef1a ch\u1ecdn \u0111\u01b0\u1ee3c c\u00e1c v\u00f9ng gen th\u00edch h\u1ee3p \u0111\u1ec3 thi\u1ebft k\u1ebf c\u1ea5u tr\u00fac gen ph\u1ee5c v\u1ee5 cho vi\u1ec7c t\u1ea1o c\u00e2y kh\u00e1ng b\u1ec7nh. \u00a0To\u00e0n b\u1ed9 qu\u00e1 tr\u00ecnh tr\u00ean c\u0169ng \u0111\u01b0\u1ee3c t\u00ednh to\u00e1n v\u00e0 m\u00f4 ph\u1ecfng tr\u00ean m\u00e1y t\u00ednh \u0111\u1ec3 c\u00f3 th\u1ec3 d\u1ef1 \u0111o\u00e1n v\u00e0 t\u1ed1i \u01b0u h\u00f3a tr\u01b0\u1edbc khi \u00e1p d\u1ee5ng v\u00e0o th\u1ef1c t\u1ebf th\u00ed nghi\u1ec7m\u2026<\/p>\n

V\u1edbi m\u1ed9t quy tr\u00ecnh kh\u00e1 ph\u1ee9c t\u1ea1p v\u1edbi r\u1ea5t nhi\u1ec1u b\u01b0\u1edbc kh\u00e1c nhau k\u00e9o d\u00e0i t\u1eeb 8 \u0111\u1ebfn 10 th\u00e1ng s\u1ebd t\u1ea1o \u0111\u01b0\u1ee3c c\u00e1c d\u00f2ng \u0111u \u0111\u1ee7 chuy\u1ec3n gen v\u1edbi hi\u1ec7u su\u1ea5t 1 \u2013 1,2%, ngh\u0129a l\u00e0 v\u1edbi 100 kh\u1ed1i m\u00f4 \u0111\u01b0a v\u00f2a chuy\u1ec3n gen m\u1edbi t\u1ea1o ra \u0111\u01b0\u1ee3c 1 c\u00e2y. T\u1eeb \u0111\u00f3, h\u1ecd \u0111em tr\u1ed3ng \u1edf v\u01b0\u1eddn c\u00e2y v\u00e0 theo d\u00f5i c\u00e1c c\u00e2y gi\u1ed1ng l\u1edbn l\u00ean.<\/p>\n

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Nh\u1eefng c\u00e2y b\u00ecnh th\u01b0\u1eddng (kh\u00f4ng chuy\u1ec3n gen) ch\u1ec9 sau 1 n\u0103m l\u00e0 b\u1ecb b\u1ec7nh, c\u00f2i c\u1ecdc. Nh\u1eefng c\u00e2y chuy\u1ec3n gen, d\u00f9 ch\u1ecbu \u00e1p l\u1ef1c b\u1ec7nh cao, nh\u01b0ng v\u1eabn kh\u00f4ng m\u1eafc b\u1ec7nh v\u00e0 cho l\u01b0\u1ee3ng qu\u1ea3 l\u1edbn h\u01a1n c\u00e1c c\u00e2y th\u00f4ng th\u01b0\u1eddng.<\/p>\n

L\u1ef1a ch\u1ecdn trong s\u1ed1 c\u00e1c c\u00e2y t\u1ed1t nh\u1ea5t, c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 c\u00f3 \u0111\u01b0\u1ee3c nh\u1eefng d\u00f2ng c\u00e2y m\u00e0 t\u1ea5t c\u1ea3 c\u00e1c \u0111\u1eddi sau \u0111\u1ec1u kh\u00e1ng b\u1ec7nh v\u00e0 cho ch\u1ea5t l\u01b0\u1ee3ng qu\u1ea3 t\u1ed1t.<\/p>\n

Mong \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng v\u00e0o th\u1ef1c t\u1ebf<\/strong><\/p>\n

Tuy \u0111\u00e3 \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u th\u00e0nh c\u00f4ng, nh\u01b0ng \u0111\u1ec3 \u0111\u01b0a \u0111\u01b0\u1ee3c v\u00e0o cho b\u00e0 con tr\u1ed3ng tr\u1ecdt, c\u00e1c nh\u00e0 khoa h\u1ecdc v\u1eabn v\u01b0\u1edbng c\u01a1 ch\u1ebf lu\u1eadt ph\u00e1p hi\u1ec7n nay, t\u1ea1i n\u01b0\u1edbc ta hi\u1ec7n m\u1edbi cho ph\u00e9p kh\u1ea3o nghi\u1ec7m 3 lo\u1ea1i c\u00e2y tr\u1ed3ng bi\u1ebfn \u0111\u1ed5i gen bao g\u1ed3m: \u0111\u1eadu t\u01b0\u01a1ng, ng\u00f4 v\u00e0 b\u00f4ng.<\/p>\n

\u0110\u00e2y c\u0169ng l\u00e0 mong m\u1ecfi c\u1ee7a b\u00e0 con n\u00f4ng d\u00e2n v\u00ec gi\u1ed1ng c\u00e2y n\u00e0o, d\u00f9 \u0111\u01b0\u1ee3c ch\u0103m s\u00f3c t\u1ed1t, c\u0169ng ch\u1ec9 c\u00f3 m\u1ed9t ng\u01b0\u1ee1ng gi\u1edbi h\u1ea1n v\u1ec1 n\u0103ng xu\u1ea5t v\u00e0 kh\u1ea3 n\u0103ng kh\u00e1ng b\u1ec7nh. N\u00ean n\u1ebfu kh\u00f4ng \u00e1p d\u1ee5ng c\u00e1c c\u00f4ng ngh\u1ec7 sinh h\u1ecdc m\u1edbi nh\u1ea5t, s\u1ebd kh\u00f3 c\u00f3 th\u1ec3 t\u1ea1o \u0111\u01b0\u1ee3c hi\u1ec7u qu\u1ea3 kinh t\u1ebf cao.<\/p>\n

PGS TS Chu Ho\u00e0ng H\u00e0 v\u00e0 c\u1ed9ng s\u1ef1 hy v\u1ecdng, k\u1ebft qu\u1ea3 nghi\u00ean c\u1ee9u c\u1ee7a \u0111\u1ec1 t\u00e0i s\u1ebd ti\u1ebfp t\u1ee5c \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n, \u0111\u01b0\u1ee3c \u0111em kh\u1ea3o nghi\u1ec7m r\u1ed9ng r\u00e3i tr\u00ean c\u00e1c c\u00e1nh \u0111\u1ed3ng, \u0111\u1ec3 c\u00f3 nh\u1eefng \u0111\u00e1nh gi\u00e1 v\u00e0 nh\u00e2n r\u1ed9ng, \u0111em l\u1ea1i \u1ea5m no cho ng\u01b0\u1eddi n\u00f4ng d\u00e2n.\/.<\/p>\n

Theo VPCT<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Hi\u1ec7n nay, c\u00e1c c\u00e2y \u0111\u1ee7 \u0111\u1ee7 tr\u1ed3ng \u1edf Vi\u1ec7t Nam, c\u1ee9 6 th\u00e1ng sau khi tr\u1ed3ng l\u00e0 l\u1ea1i b\u1ecb b\u1ec7nh virus \u0111\u1ed1m v\u00f2ng, khi\u1ebfn c\u00e2y c\u00f2i c\u1ecdc, kh\u00f4ng ra \u0111\u01b0\u1ee3c nhi\u1ec1u qu\u1ea3. V\u00ec th\u1ebf, ng\u01b0\u1eddi tr\u1ed3ng c\u1ee9 sau 1 v\u1ee5 th\u01b0\u1eddng ph\u1ea3i ch\u1eb7t \u0111i tr\u1ed3ng l\u1ea1i c\u00e2y m\u1edbi. \u0110\u00f3 \u0111\u00f3, m\u1ea5t r\u1ea5t nhi\u1ec1u th\u1eddi gian, […]\n","protected":false},"author":1,"featured_media":1041,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[86],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/posts\/5979"}],"collection":[{"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/comments?post=5979"}],"version-history":[{"count":0,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/posts\/5979\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/media\/1041"}],"wp:attachment":[{"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/media?parent=5979"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/categories?post=5979"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/tags?post=5979"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}