{"id":6656,"date":"2014-06-01T10:18:29","date_gmt":"2014-06-01T03:18:29","guid":{"rendered":"http:\/\/antoansinhhoc.vn\/?p=1773"},"modified":"2014-06-01T10:18:29","modified_gmt":"2014-06-01T03:18:29","slug":"protein-milk-bundle-cai-thien-chat-luong-dinh-duong-cua-hat-dau-nanh-transgenic","status":"publish","type":"post","link":"https:\/\/nbca.gov.vn\/protein-milk-bundle-cai-thien-chat-luong-dinh-duong-cua-hat-dau-nanh-transgenic\/","title":{"rendered":"Protein \u201cMilk-Bundle\u201d c\u1ea3i thi\u1ec7n ch\u1ea5t l\u01b0\u1ee3ng dinh d\u01b0\u1ee1ng c\u1ee7a h\u1ea1t \u0111\u1eadu n\u00e0nh transgenic"},"content":{"rendered":"
C\u00e1c nh\u00e0 khoa h\u1ecdc tr\u00ean th\u1ebf gi\u1edbi \u0111\u00e3 c\u00f3 nh\u1eefng ti\u1ebfn b\u1ed9 v\u01b0\u1ee3t b\u1eadc trong k\u1ef9 thu\u1eadt di truy\u1ec1n \u0111\u1ec3 c\u1ea3i thi\u1ec7n ch\u1ea5t l\u01b0\u1ee3ng dinh d\u01b0\u1ee1ng protein trong h\u1ea1t \u0111\u1eadu n\u00e0nh
\n<\/span>\u0110\u0103ng ng\u00e0y 01-06-2014<\/span> trong chuy\u00ean m\u1ee5c Tin th\u1ebf gi\u1edbi<\/a><\/div>\n
\n

\"\"Ng\u01b0\u1eddi ta \u0111\u00e3 c\u00f3 nh\u1eefng ti\u1ebfn b\u1ed9 v\u01b0\u1ee3t b\u1eadc trong k\u1ef9 thu\u1eadt di truy\u1ec1n (genetic engineering<\/a>) \u0111\u1ec3 c\u1ea3i thi\u1ec7n ch\u1ea5t l\u01b0\u1ee3ng dinh d\u01b0\u1ee1ng protein trong h\u1ea1t \u0111\u1eadu n\u00e0nh. Tuy nhi\u00ean, nh\u1eefng ti\u1ebfn b\u1ed9 \u1ea5y ch\u01b0a \u0111\u1ee7 \u0111\u00e1p \u1ee9ng v\u1edbi y\u00eau c\u1ea7u dinh d\u01b0\u1ee1ng trong l\u01b0\u01a1ng th\u1ef1c v\u00e0 th\u1ef1c ph\u1ea9m. Nghi\u00ean c\u1ee9u g\u1ea7n \u0111\u00e2y nh\u1eb1m m\u1ee5c \u0111\u00edch gia t\u0103ng h\u00e0m l\u01b0\u1ee3ng amino acid gi\u00e0u l\u01b0u hu\u1ef3nh trong protein \u0111\u1eadu n\u00e0nh th\u00f4ng qua s\u1ef1 th\u1ec3 hi\u1ec7n gen m\u00e3 h\u00f3a protein MB-16 de novo<\/em><\/strong> thu\u1ed9c \u201cMilk Bundle protein<\/strong>\u201d, trong h\u1ea1t \u0111\u1eadu n\u00e0nh transgenic. Gen MB-16<\/em>, c\u00f3 ngu\u1ed3n g\u1ed1c t\u1eeb vi khu\u1ea9n c\u00f3 trong d\u1ea1 c\u1ecf c\u1ee7a th\u00fa nhai l\u1ea1i, \u0111\u01b0\u1ee3c chuy\u1ec3n v\u00e0o b\u1ed9 genome c\u1ee7a \u0111\u1eadu n\u00e0nh (Glycine max<\/em> (L.) Merrill) nh\u1eb1m c\u1ea3i ti\u1ebfn ph\u1ea9m ch\u1ea5t dinh d\u01b0\u1ee1ng c\u1ee7a h\u1ea1t. MB-16<\/em> m\u00e3 h\u00f3a m\u1ed9t protein de novo<\/em> r\u1ea5t gi\u00e0u amino acid c\u1ea7n thi\u1ebft EAA (essential amino acids) nh\u01b0 methionine, threonine, lysine <\/strong>v\u00e0 leucine<\/strong>. Thi\u1ebft k\u1ebf vec t\u01a1 chuy\u1ec3n n\u1ea1p gen b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng codon bias<\/strong> c\u1ee7a \u0111\u1eadu n\u00e0nh, c\u00f3 ho\u1eb7c kh\u00f4ng c\u00f3 tr\u00ecnh t\u1ef1KDELER<\/strong>. C\u00e2y s\u1ef1 ki\u1ec7n (transformed events) cho th\u1ea5y ch\u00fang c\u00f3 c\u00f9ng ph\u00e2n t\u1eed trong phi\u00ean m\u00e3 (transcription pattern) nh\u01b0 nh\u1eefng g\u00ec m\u00e0 c\u00e2y \u0111\u1eadu n\u00e0nh \u01b0a chu\u1ed9ng codon \u0111\u1eb7c th\u00f9 c\u1ee7a ch\u00fang, nh\u01b0ng m\u1ee9c \u0111\u1ed9 c\u00e1c ph\u00e2n t\u1eed transcript bi\u1ec3u th\u1ecb \u00edt h\u01a1n \u1edf t\u1eebng giai \u0111o\u1ea1n ph\u00e1t tri\u1ec3n. M\u1ee9c \u0111\u1ed9 protein MB-16 \u0111\u1ea1t cao nh\u1ea5t trong giai \u0111o\u1ea1n h\u1ea1t \u0111\u1eadu n\u00e0nh ho\u00e0n to\u00e0n c\u00f2n xanh, v\u00e0 bi\u1ebfn m\u1ea5t khi h\u1ea1t tr\u01b0\u1edfng th\u00e0nh. Tuy v\u1eady, ph\u00e2n t\u00edch amino acid c\u1ee7a nh\u1eefng h\u1ea1t transgenic tr\u01b0\u1edfng th\u00e0nh cho th\u1ea5y c\u00f3 s\u1ef1 gia t\u0103ng \u0111\u00e1ng k\u1ec3 h\u00e0m l\u01b0\u1ee3ng methionine v\u00e0 cysteine so v\u1edbi b\u1ed1 m\u1eb9. \u0110i\u1ec1u n\u00e0y cho th\u1ea5y r\u1eb1ng MB-16 l\u00e0m t\u0103ng c\u00e1c sulfur amino acids<\/strong>, c\u1ea3i thi\u1ec7n \u0111\u01b0\u1ee3c ph\u1ed5 EAA trong h\u1ea1t, x\u00e1c \u0111\u1ecbnh gen t\u1ed5ng h\u1ee3p c\u00f3 t\u00ednh ch\u1ea5t de novo<\/em> gi\u00fap c\u00e2y t\u0103ng c\u01b0\u1eddng ch\u1ea5t l\u01b0\u1ee3ng dinh d\u01b0\u1ee1ng c\u1ee7a \u0111\u1eadu n\u00e0nh.<\/p>\n

Xem http:\/\/link.springer.com\/article\/10.1007\/s11248-013-9777-5\/fulltext.html<\/a>.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

C\u00e1c nh\u00e0 khoa h\u1ecdc tr\u00ean th\u1ebf gi\u1edbi \u0111\u00e3 c\u00f3 nh\u1eefng ti\u1ebfn b\u1ed9 v\u01b0\u1ee3t b\u1eadc trong k\u1ef9 thu\u1eadt di truy\u1ec1n \u0111\u1ec3 c\u1ea3i thi\u1ec7n ch\u1ea5t l\u01b0\u1ee3ng dinh d\u01b0\u1ee1ng protein trong h\u1ea1t \u0111\u1eadu n\u00e0nh \u0110\u0103ng ng\u00e0y 01-06-2014 trong chuy\u00ean m\u1ee5c Tin th\u1ebf gi\u1edbi Ng\u01b0\u1eddi ta \u0111\u00e3 c\u00f3 nh\u1eefng ti\u1ebfn b\u1ed9 v\u01b0\u1ee3t b\u1eadc trong k\u1ef9 thu\u1eadt di truy\u1ec1n (genetic […]\n","protected":false},"author":1,"featured_media":6366,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[87],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/posts\/6656"}],"collection":[{"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/comments?post=6656"}],"version-history":[{"count":0,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/posts\/6656\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/media\/6366"}],"wp:attachment":[{"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/media?parent=6656"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/categories?post=6656"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/tags?post=6656"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}