{"id":6664,"date":"2014-09-24T09:48:33","date_gmt":"2014-09-24T02:48:33","guid":{"rendered":"http:\/\/antoansinhhoc.vn\/?p=1626"},"modified":"2014-09-24T09:48:33","modified_gmt":"2014-09-24T02:48:33","slug":"nghien-cuu-ve-sieu-chuoi-sua-doi-di-truyen","status":"publish","type":"post","link":"https:\/\/nbca.gov.vn\/nghien-cuu-ve-sieu-chuoi-sua-doi-di-truyen\/","title":{"rendered":"Nghi\u00ean c\u1ee9u v\u1ec1 \u201csi\u00eau chu\u1ed1i\u201d s\u1eeda \u0111\u1ed5i di truy\u1ec1n"},"content":{"rendered":"
Nh\u1eefng ti\u1ebfn\u00a0b\u1ed9 m\u1edbi cho ph\u00e9p s\u1eeda \u0111\u1ed5i ch\u00ednh x\u00e1c h\u1ec7 gien hi\u1ec7n \u0111ang \u0111\u01b0a ra kh\u1ea3 n\u0103ng l\u00e0 tr\u00e1i c\u00e2y v\u00e0 c\u00e1c lo\u1ea1i c\u00e2y tr\u1ed3ng kh\u00e1c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c c\u1ea3i thi\u1ec7n di truy\u1ec1n m\u00e0 kh\u00f4ng c\u1ea7n ph\u1ea3i \u0111\u01b0a v\u00e0o c\u00e1c gien ngo\u00e0i, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u cho bi\u1ebft trong \u1ea5n ph\u1ea9m Trends in Biotechnology c\u1ee7a Cell Press xu\u1ea5t b\u1ea3n ng\u00e0y 13\/8.<\/span><\/div>\n
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V\u1edbi nh\u1eadn th\u1ee9c v\u1ec1 \u0111i\u1ec1u khi\u1ebfn nh\u1eefng c\u00f4ng ngh\u1ec7 sinh h\u1ecdc m\u1edbi m\u1ebb v\u00e0 kh\u00e1c bi\u1ec7t, tr\u00e1i c\u00e2y \u0111\u01b0\u1ee3c s\u1eeda \u0111\u1ed5i di truy\u1ec1n c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c x\u00e3 h\u1ed9i ch\u1ea5p nh\u1eadn nhi\u1ec1u h\u01a1n so v\u1edbi c\u00e1c c\u00e2y tr\u1ed3ng bi\u1ebfn \u0111\u1ed5i gien (GMO) \u0111\u1ebfn nay \u0111\u00e3 nh\u1eadn \u0111\u01b0\u1ee3c, \u0111\u1eb7c bi\u1ec7t l\u00e0 \u1edf ch\u00e2u \u00c2u. \u0110i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 c\u00f3 ngh\u0129a l\u00e0 c\u00e1c phi\u00ean b\u1ea3n s\u1eeda \u0111\u1ed5i v\u1ec1 di truy\u1ec1n c\u1ee7a c\u00e2y tr\u1ed3ng bi\u1ebfn \u0111\u1ed5i gien nh\u01b0 “si\u00eau chu\u1ed1i” t\u1ea1o ra nhi\u1ec1u vitamin A h\u01a1n v\u00e0 t\u00e1o kh\u00f4ng chuy\u1ec3n m\u00e0u n\u00e2u khi c\u1eaft, l\u00e0 m\u1ed9t trong s\u1ed1 c\u00e1c \u0111\u1eb7c \u0111i\u1ec3m m\u1edbi l\u1ea1 kh\u00e1c, c\u00f3 th\u1ec3 s\u1ebd xu\u1ea5t hi\u1ec7n tr\u00ean c\u00e1c k\u1ec7 h\u00e0ng.<\/p>\n

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“Vi\u1ec7c tr\u00e1nh \u0111\u01b0a v\u00e0o c\u00e1c gien ngo\u00e0i khi\u1ebfn c\u00e2y tr\u1ed3ng \u0111\u01b0\u1ee3c s\u1eeda \u0111\u1ed5i di truy\u1ec1n tr\u1edf n\u00ean \u201ct\u1ef1 nhi\u00ean\u201d h\u01a1n c\u00e2y tr\u1ed3ng bi\u1ebfn \u0111\u1ed5i gien thu \u0111\u01b0\u1ee3c b\u1eb1ng c\u00e1ch \u0111\u01b0a v\u00e0o c\u00e1c gen ngo\u00e0i”, Chidananda Nagamangala Kanchiswamy c\u1ee7a Vi\u1ec7n Istituto Agrario San Michele \u1edf \u00dd cho bi\u1ebft.<\/div>\n
Ch\u1eb3ng h\u1ea1n nh\u01b0 nh\u1eefng thay \u0111\u1ed5i \u0111\u1ed1i v\u1edbi c\u00e1c \u0111\u1eb7c t\u00ednh c\u1ee7a tr\u00e1i c\u00e2y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n th\u00f4ng qua c\u1ea3i ti\u1ebfn di truy\u1ec1n nh\u1ecf \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf \u0111\u1ec3 t\u0103ng ho\u1eb7c gi\u1ea3m s\u1ed1 l\u01b0\u1ee3ng c\u00e1c th\u00e0nh ph\u1ea7n t\u1ef1 nhi\u00ean m\u00e0 t\u1ebf b\u00e0o th\u1ef1c v\u1eadt t\u1ea1o ra. S\u1eeda \u0111\u1ed5i b\u1ed9 gien c\u1ee7a tr\u00e1i c\u00e2y ng\u00e0y nay \u0111\u00e3 c\u00f3 th\u1ec3 th\u1ef1c hi\u1ec7n \u0111\u01b0\u1ee3c nh\u1edd s\u1ef1 ra \u0111\u1eddi c\u1ee7a c\u00e1c c\u00f4ng c\u1ee5 m\u1edbi: CRISPR, TALEN, v\u00e0 c\u0169ng nh\u1edd nh\u1eefng ki\u1ebfn th\u1ee9c s\u00e2u r\u1ed9ng v\u00e0 ng\u00e0y c\u00e0ng \u0111\u01b0\u1ee3c t\u0103ng c\u01b0\u1eddng v\u1ec1 h\u1ec7 gien tr\u00e1i c\u00e2y.<\/div>\n
Cho \u0111\u1ebfn nay, c\u00e1c c\u00f4ng c\u1ee5 ch\u1ec9nh s\u1eeda v\u1eabn ch\u01b0a \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng cho vi\u1ec7c s\u1eeda \u0111\u1ed5i di truy\u1ec1n c\u1ee7a c\u00e2y \u0103n qu\u1ea3. H\u1ea7u h\u1ebft c\u00e1c c\u00e2y \u0103n qu\u1ea3 chuy\u1ec3n gien \u0111\u00e3 \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng m\u1ed9t lo\u1ea1i vi khu\u1ea9n th\u1ef1c v\u1eadt \u0111\u1ec3 \u0111\u01b0a v\u00e0o c\u00e1c gien ngo\u00e0i, v\u00e0 ch\u1ec9 c\u00f3 \u0111u \u0111\u1ee7 l\u00e0 \u0111\u00e3 \u0111\u01b0\u1ee3c th\u01b0\u01a1ng m\u1ea1i h\u00f3a m\u1ed9t ph\u1ea7n b\u1edfi quy \u0111\u1ecbnh nghi\u00eam ng\u1eb7t t\u1ea1i Li\u00ean minh ch\u00e2u \u00c2u (EU). C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u cho bi\u1ebft r\u1eb1ng, c\u00e2y tr\u1ed3ng \u0111\u01b0\u1ee3c s\u1eeda \u0111\u1ed5i gien, thay \u0111\u1ed5i th\u00f4ng qua vi\u1ec7c ch\u00e8n, x\u00f3a, ho\u1eb7c thay th\u1ebf c\u00e1c gien \u0111\u01b0\u1ee3c quan t\u00e2m hi\u1ec7n c\u00f3, th\u1eadm ch\u00ed c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c coi l\u00e0 kh\u00f4ng bi\u1ebfn \u0111\u1ed5i gien, t\u00f9y thu\u1ed9c v\u00e0o gi\u1ea3i th\u00edch c\u1ee7a \u1ee6y ban ch\u00e2u \u00c2u v\u00e0 th\u00e0nh vi\u00ean c\u01a1 quan qu\u1ea3n l\u00fd nh\u00e0 n\u01b0\u1edbc c\u1ee7a EU.<\/div>\n
C\u00e2y \u0103n qu\u1ea3 ch\u1ec9 l\u00e0 m\u1ed9t v\u00ed d\u1ee5 cho h\u00e0ng t\u00e1 c\u00e1c \u1ee9ng d\u1ee5ng trong t\u01b0\u01a1ng lai c\u00f3 th\u1ec3 th\u1ef1c hi\u1ec7n cho c\u00e1c th\u1ef1c th\u1ec3 s\u1eeda \u0111\u1ed5i di truy\u1ec1n (GEOs), Kanchiswamy v\u00e0 \u0111\u1ed3ng nghi\u1ec7p c\u1ee7a \u00f4ng cho bi\u1ebft. \u0110i\u1ec1u \u0111\u00f3 s\u1ebd m\u1edf ra c\u00e1nh c\u1eeda cho s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a c\u00e1c lo\u1ea1i c\u00e2y tr\u1ed3ng c\u00f3 ch\u1ea5t l\u01b0\u1ee3ng cao v\u00e0 c\u00f3 l\u1ebd s\u1ebd th\u1eeba nh\u1eadn t\u00ednh th\u01b0\u01a1ng m\u1ea1i h\u00f3a c\u1ee7a ch\u00fang ngay c\u1ea3 \u1edf c\u00e1c qu\u1ed1c gia m\u00e0 c\u00e2y tr\u1ed3ng bi\u1ebfn \u0111\u1ed5i gien cho \u0111\u1ebfn nay v\u1eabn \u0111ang b\u1ecb ch\u1ec9 tr\u00edch gay g\u1eaft v\u00e0 \u0111ang l\u00e0 v\u1ea5n \u0111\u1ec1 tranh c\u00e3i.<\/div>\n
“Ch\u00fang t\u00f4i mu\u1ed1n m\u1ecdi ng\u01b0\u1eddi hi\u1ec3u r\u1eb1ng c\u00e2y tr\u1ed3ng nh\u00e2n gi\u1ed1ng nh\u1edd c\u00f4ng ngh\u1ec7 sinh h\u1ecdc kh\u00f4ng ch\u1ec9 gi\u1edbi h\u1ea1n l\u00e0 c\u00e2y tr\u1ed3ng bi\u1ebfn \u0111\u1ed5i gien GMO”, \u00f4ng n\u00f3i. “Chuy\u1ec3n gien ngo\u00e0i v\u00e0o c\u00e2y tr\u1ed3ng l\u00e0 b\u01b0\u1edbc \u0111\u1ea7u ti\u00ean \u0111\u1ec3 c\u1ea3i ti\u1ebfn c\u00e2y tr\u1ed3ng c\u1ee7a ch\u00fang ta, nh\u01b0ng GEOs n\u1ed5i l\u00ean nh\u01b0 l\u00e0 m\u1ed9t chi\u1ebfn l\u01b0\u1ee3c \u201ct\u1ef1 nhi\u00ean\u201d \u0111\u1ec3 s\u1eed d\u1ee5ng c\u00f4ng ngh\u1ec7 sinh h\u1ecdc cho m\u1ed9t ng\u00e0nh n\u00f4ng nghi\u1ec7p b\u1ec1n v\u1eefng trong t\u01b0\u01a1ng lai”.<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Nh\u1eefng ti\u1ebfn\u00a0b\u1ed9 m\u1edbi cho ph\u00e9p s\u1eeda \u0111\u1ed5i ch\u00ednh x\u00e1c h\u1ec7 gien hi\u1ec7n \u0111ang \u0111\u01b0a ra kh\u1ea3 n\u0103ng l\u00e0 tr\u00e1i c\u00e2y v\u00e0 c\u00e1c lo\u1ea1i c\u00e2y tr\u1ed3ng kh\u00e1c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c c\u1ea3i thi\u1ec7n di truy\u1ec1n m\u00e0 kh\u00f4ng c\u1ea7n ph\u1ea3i \u0111\u01b0a v\u00e0o c\u00e1c gien ngo\u00e0i, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u cho bi\u1ebft trong \u1ea5n ph\u1ea9m Trends in Biotechnology c\u1ee7a […]\n","protected":false},"author":1,"featured_media":6348,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[87],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/posts\/6664"}],"collection":[{"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/comments?post=6664"}],"version-history":[{"count":0,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/posts\/6664\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/media\/6348"}],"wp:attachment":[{"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/media?parent=6664"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/categories?post=6664"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/tags?post=6664"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}