{"id":6696,"date":"2015-05-02T09:19:04","date_gmt":"2015-05-02T02:19:04","guid":{"rendered":"http:\/\/antoansinhhoc.vn\/?p=1498"},"modified":"2015-05-02T09:19:04","modified_gmt":"2015-05-02T02:19:04","slug":"phuong-phap-tim-cac-dot-bien-xau-co-the-giup-tang-san-luong-ngo","status":"publish","type":"post","link":"https:\/\/nbca.gov.vn\/phuong-phap-tim-cac-dot-bien-xau-co-the-giup-tang-san-luong-ngo\/","title":{"rendered":"Ph\u01b0\u01a1ng ph\u00e1p t\u00ecm c\u00e1c \u0111\u1ed9t bi\u1ebfn x\u1ea5u c\u00f3 th\u1ec3 gi\u00fap t\u0103ng s\u1ea3n l\u01b0\u1ee3ng ng\u00f4"},"content":{"rendered":"<div class=\"TomTat clearfix\">\n<p><span id=\"ArticalDetail1_lblTeaser\" class=\"OverollContentDesc\">C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u Cornell \u0111\u00e3 ph\u00e1t tri\u1ec3n m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p d\u1ef1 \u0111o\u00e1n c\u00e1c \u0111\u1ed9t bi\u1ebfn x\u1ea5u trong h\u1ec7 gien c\u1ee7a ng\u00f4, gi\u00fap gi\u1ea3i quy\u1ebft m\u1ed9t th\u00e1ch th\u1ee9c l\u1edbn cho c\u00e1c nh\u00e0 lai t\u1ea1o trong vi\u1ec7c t\u00ecm ra c\u00e1c gi\u1ed1ng c\u00e2y tr\u1ed3ng t\u1ed1t h\u01a1n nh\u1eb1m \u0111\u00e1p \u1ee9ng nhu c\u1ea7u l\u01b0\u01a1ng th\u1ef1c trong b\u1ed1i c\u1ea3nh d\u00e2n s\u1ed1 th\u1ebf gi\u1edbi ng\u00e0y c\u00e0ng t\u0103ng cao. C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 t\u00ecm th\u1ea5y c\u00e1c khu v\u1ef1c c\u1ee7a b\u1ed9 gien c\u00f3 nh\u1eefng ADN kh\u00f4ng mong mu\u1ed1n.\u00a0<\/span><\/p>\n<\/div>\n<div class=\"NoiDungBai\">\n<div>\u0110\u1ed1i v\u1edbi t\u1ea5t c\u1ea3 c\u00e1c gien c\u00f3 ch\u1ee9a m\u1ed9t \u0111\u1eb7c \u0111i\u1ec3m mong mu\u1ed1n, nhi\u1ec1u \u0111\u1ed9t bi\u1ebfn kh\u00f4ng mong mu\u1ed1n l\u1ea1i xu\u1ea5t hi\u1ec7n \u2013 \u0111\u00e2y l\u00e0 m\u1ed9t tr\u1edf ng\u1ea1i chung cho c\u00e1c nh\u00e0 lai t\u1ea1o gi\u1ed1ng. Khi bi\u1ebft ch\u00ednh x\u00e1c v\u1ecb tr\u00ed c\u1ee7a nh\u1eefng \u0111\u1ed9t bi\u1ebfn x\u1ea5u trong h\u1ec7 gien, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u c\u00f3 th\u1ec3 \u00e1p d\u1ee5ng c\u00f4ng ngh\u1ec7 ch\u1ec9nh s\u1eeda gien m\u1edbi cho ph\u00e9p c\u1eaft gi\u1ea3m ch\u00ednh x\u00e1c c\u00e1c l\u1ed7i n\u00e0y.<\/div>\n<div><\/div>\n<div>Edward Buckler, nh\u00e0 nghi\u00ean c\u1ee9u di truy\u1ec1n h\u1ecdc thu\u1ed9c B\u1ed9 N\u00f4ng nghi\u1ec7p M\u1ef9 (USDA) cho bi\u1ebft: \u201cC\u00f4ng ngh\u1ec7 n\u00e0y cho ph\u00e9p ch\u00fang ta nh\u1eadn ra nh\u1eefng \u0111\u1ed9t bi\u1ebfn x\u1ea5u v\u00e0 lo\u1ea1i b\u1ecf ch\u00fang ra kh\u1ecfi h\u1ec7 gien\u201d.<\/div>\n<div><\/div>\n<div>V\u1edbi vi\u1ec7c ch\u1ec9nh s\u1eeda b\u1ed9 gien, c\u00e1c gien kh\u00f4ng mong mu\u1ed1n c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c thay th\u1ebf b\u1eb1ng m\u1ed9t bi\u1ebfn th\u1ec3 t\u1ed1t. Nghi\u00ean c\u1ee9u t\u1eadp trung v\u00e0o vi\u1ec7c t\u00e1i t\u1ed5 h\u1ee3p, m\u1ed9t qu\u00e1 tr\u00ecnh x\u00e1o tr\u1ed9n gien t\u1ef1 nhi\u00ean, trong \u0111\u00f3 c\u00e1c ph\u1ea7n c\u1ee7a b\u1ed9 gien t\u1eeb b\u1ed1 m\u1eb9 \u0111\u01b0\u1ee3c \u0111\u01b0a v\u00e0o th\u1ebf h\u1ec7 con.<\/div>\n<div><\/div>\n<div>Eli Rodgers-Melnick, \u0111\u1ed3ng t\u00e1c gi\u1ea3 nghi\u00ean c\u1ee9u cho bi\u1ebft: \u201cN\u1ebfu s\u1ef1 t\u00e1i t\u1ed5 h\u1ee3p kh\u00f4ng x\u1ea3y ra trong m\u1ed9t khu v\u1ef1c c\u1ee7a ADN, c\u00e1c \u0111\u1ed9t bi\u1ebfn t\u1ed1t kh\u00f4ng c\u00f3 c\u01a1 h\u1ed9i \u0111\u1ec3 h\u1ee3p l\u1ea1i v\u1edbi nhau. \u0110\u1ed3ng th\u1eddi, \u0111\u1ed9t bi\u1ebfn x\u1ea5u c\u00f3 th\u1ec3 b\u1ecb l\u1eabn v\u00e0o c\u00e1c \u0111\u1ed9t bi\u1ebfn t\u1ed1t\u201d.<\/div>\n<div><\/div>\n<div>Trong nghi\u00ean c\u1ee9u n\u00e0y, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 ph\u00e2n t\u00edch c\u00e1c d\u1ea5u hi\u1ec7u trong b\u1ed9 gien c\u1ee7a 7.000 gi\u1ed1ng ng\u00f4 \u0111\u1ea1i di\u1ec7n cho s\u1ef1 \u0111a d\u1ea1ng c\u1ee7a c\u00e2y ng\u00f4 &#8211; \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh n\u01a1i s\u1ef1 lai gi\u1ed1ng x\u1ea3y ra trong \u0111\u00f3 c\u00e1c khu v\u1ef1c c\u1ee7a b\u1ed9 gien c\u00f3 th\u1ec3 h\u1ee3p l\u1ea1i v\u1edbi nhau th\u00e0nh m\u1ed9t nh\u00f3m. C\u00e1c nh\u00e0 khoa h\u1ecdc ph\u00e1t hi\u1ec7n ra qu\u00e1 tr\u00ecnh n\u00e0y r\u1ea5t gi\u1ed1ng nhau tr\u00ean t\u1ea5t c\u1ea3 c\u00e1c gi\u1ed1ng ng\u00f4.<\/div>\n<div><\/div>\n<div>C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u c\u0169ng ph\u00e1t hi\u1ec7n ra r\u1eb1ng c\u00e1c v\u00f9ng c\u1ee7a b\u1ed9 gien ng\u00f4 v\u1edbi t\u1ef7 l\u1ec7 t\u00e1i t\u1ed5 h\u1ee3p th\u1ea5p nh\u1ea5t c\u0169ng ch\u1ee9a s\u1ed1 l\u01b0\u1ee3ng l\u1edbn nh\u1ea5t c\u1ee7a \u0111\u1ed9t bi\u1ebfn x\u1ea5u. \u0110i\u1ec1u n\u00e0y c\u00f3 ngh\u0129a l\u00e0 c\u00e1c ph\u1ea7n c\u1ee7a b\u1ed9 gien ng\u00f4 c\u00f3 ch\u1ee9a nhi\u1ec1u \u0111\u1ed9t bi\u1ebfn kh\u00f4ng mong mu\u1ed1n c\u0169ng s\u1ebd l\u00e0 c\u00e1c khu v\u1ef1c kh\u00f3 kh\u0103n nh\u1ea5t \u0111\u1ec3 c\u1ea3i t\u1ea1o b\u1eb1ng c\u00e1c k\u1ef9 thu\u1eadt lai t\u1ea1o th\u00f4ng th\u01b0\u1eddng.<\/div>\n<div><\/div>\n<div>C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u l\u01b0u \u00fd r\u1eb1ng ch\u1ec9nh s\u1eeda gien l\u00e0 kh\u00e1c v\u1edbi bi\u1ebfn \u0111\u1ed5i gien (vi\u1ec7c \u0111\u01b0a c\u00e1c gien t\u1eeb b\u00ean ngo\u00e0i v\u00e0o h\u1ec7 gien). Nh\u00e0 nghi\u00ean c\u1ee9u Buckler cho bi\u1ebft: \u201cCh\u00fang t\u00f4i kh\u00f4ng gi\u1edbi thi\u1ec7u c\u00e1c gien m\u1edbi m\u00e0 s\u1eeda ch\u1eefa ch\u00ednh x\u00e1c nh\u1eefng \u0111\u1ed9t bi\u1ebfn x\u1ea5u \u1edf b\u1ed9 gien c\u1ee7a c\u00e2y ng\u00f4. M\u1ed7i gi\u1ed1ng ng\u00f4 c\u00f3 v\u00e0i tr\u0103m \u0111\u1ebfn h\u00e0ng ng\u00e0n \u0111\u1ed9t bi\u1ebfn x\u1ea5u\u201d. C\u00e1c nh\u00e0 khoa h\u1ecdc hy v\u1ecdng k\u1ef9 thu\u1eadt n\u00e0y s\u1ebd gi\u00fap t\u0103ng s\u1ea3n l\u01b0\u1ee3ng ng\u00f4 \u2013 m\u1ed9t trong nh\u1eefng lo\u1ea1i c\u00e2y l\u01b0\u01a1ng th\u1ef1c quan tr\u1ecdng nh\u1ea5t tr\u00ean th\u1ebf gi\u1edbi.<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u Cornell \u0111\u00e3 ph\u00e1t tri\u1ec3n m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p d\u1ef1 \u0111o\u00e1n c\u00e1c \u0111\u1ed9t bi\u1ebfn x\u1ea5u trong h\u1ec7 gien c\u1ee7a ng\u00f4, gi\u00fap gi\u1ea3i quy\u1ebft m\u1ed9t th\u00e1ch th\u1ee9c l\u1edbn cho c\u00e1c nh\u00e0 lai t\u1ea1o trong vi\u1ec7c t\u00ecm ra c\u00e1c gi\u1ed1ng c\u00e2y tr\u1ed3ng t\u1ed1t h\u01a1n nh\u1eb1m \u0111\u00e1p \u1ee9ng nhu c\u1ea7u l\u01b0\u01a1ng th\u1ef1c trong b\u1ed1i c\u1ea3nh d\u00e2n [&#8230;]\n","protected":false},"author":1,"featured_media":1517,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[87],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/posts\/6696"}],"collection":[{"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/comments?post=6696"}],"version-history":[{"count":0,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/posts\/6696\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/media\/1517"}],"wp:attachment":[{"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/media?parent=6696"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/categories?post=6696"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/tags?post=6696"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}