{"id":6778,"date":"2016-08-12T08:08:33","date_gmt":"2016-08-12T01:08:33","guid":{"rendered":"http:\/\/antoansinhhoc.vn\/?p=2497"},"modified":"2016-08-12T08:08:33","modified_gmt":"2016-08-12T01:08:33","slug":"gen-ma-hoa-sumo-protease-ots1-dieu-khien-chong-chiu-man-cua-cay-lua","status":"publish","type":"post","link":"https:\/\/nbca.gov.vn\/gen-ma-hoa-sumo-protease-ots1-dieu-khien-chong-chiu-man-cua-cay-lua\/","title":{"rendered":"Gen m\u00e3 h\u00f3a SUMO PROTEASE (OTS1) \u0111i\u1ec1u khi\u1ec3n ch\u1ed1ng ch\u1ecbu m\u1eb7n c\u1ee7a c\u00e2y l\u00faa"},"content":{"rendered":"
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M\u1eb7n l\u00e0 m\u1ed9t trong nh\u1eefng lo\u1ea1i h\u00ecnh g\u00e2y stress ch\u1ee7 y\u1ebfu trong m\u00f4i tr\u01b0\u1eddng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn n\u0103ng su\u1ea5t l\u00faa tr\u00ean to\u00e0n c\u1ea7u. C\u1ea3i ti\u1ebfn gi\u1ed1ng l\u00faa ch\u1ed1ng ch\u1ecbu m\u1eb7n l\u00e0 n\u1ed9i dung \u0111\u01b0\u1ee3c xem x\u00e9t c\u1ea5p thi\u1ebft ph\u1ee5c v\u1ee5 chi\u1ebfn l\u01b0\u1ee3c s\u1ea3n xu\u1ea5t l\u01b0\u01a1ng th\u1ef1c b\u1ec1n v\u1eefng.<\/span>\u0110\u0103ng ng\u00e0y 09-06-2016<\/span> trong chuy\u00ean m\u1ee5c Tin th\u1ebf gi\u1edbi<\/a><\/p>\n<\/div>\n

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S\u1ef1 c\u1ea3i bi\u00ean h\u1eadu gi\u1ea3i m\u00e3 c\u1ee7a nh\u1eefng proteins \u1ea3nh h\u01b0\u1edfng m\u1ed9t c\u00e1ch lan r\u1ed9ng \u0111\u1ed1i v\u1edbi k\u1ebft qu\u1ea3 \u0111a d\u1ea1ng b\u1ed9 proteome, l\u00e0m gia t\u0103ng t\u00ednh ch\u1ea5t ch\u1ee9c n\u0103ng c\u1ee7a ch\u00fang v\u00e0 cho ph\u00e9p c\u00f3 nh\u1eefng ph\u1ea3n \u1ee9ng nhanh \u0111\u1ed1i v\u1edbi c\u00e1c stress do ngo\u1ea1i c\u1ea3nh g\u00e2y ra, \u1edf m\u1ee9c \u0111\u1ed9 r\u1ebb ti\u1ec1n nh\u1ea5t trong c\u00f4ng ngh\u1ec7 t\u1ebf b\u00e0o. Vi\u1ec7c c\u1ea3i bi\u00ean SUMO theo c\u00e1ch h\u1eadu gi\u1ea3i m\u00e3 c\u1ee7a nh\u1eefng protein c\u00f3 t\u00ednh ch\u1ea5t nh\u01b0 \u201cc\u01a1 ch\u1ea5t c\u1ea7n thi\u1ebft\u201d l\u00e0 m\u1ed9t ti\u1ebfn tr\u00ecnh h\u1ebft s\u1ee9c t\u00edch c\u1ef1c \u0111\u01b0\u1ee3c \u0111i\u1ec1u khi\u1ec3n b\u1edfi s\u1ef1 c\u00e2n b\u1eb1ng gi\u1eefa nh\u1eefng ho\u1ea1t \u0111\u1ed9ng c\u1ee7a SUMO E3 ligases v\u00e0 s\u1ef1 kh\u00f4ng ti\u1ebfp h\u1ee3p c\u1ee7a nh\u1eefng SUMO proteases.<\/p>\n

G\u1ea7n \u0111\u00e2y, s\u1ef1 ti\u1ebfp h\u1ee3p c\u1ee7a nh\u1eefng protein SUMO (Small Ubiquitin like Modifier) xu\u1ea5t hi\u1ec7n nh\u01b0 m\u1ed9t ph\u00e2n t\u1eed \u0111\u00f3ng vai tr\u00f2 \u201cregulator\u201d c\u00f3 \u1ea3nh h\u01b0\u1edfng s\u00e2u r\u1ed9ng \u0111\u1ebfn ti\u1ebfn tr\u00ecnh truy\u1ec1n t\u00edn hi\u1ec7u c\u00e1c stress trong c\u00e2y m\u00f4 h\u00ecnh Arabidopsis. Tuy nhi\u00ean, s\u1ef1 ki\u1ec7n \u201cmethyl h\u00f3a\u201d SUMO v\u1eabn c\u00f2n \u1edf m\u1ee9c \u0111\u1ed9 \u0111ang nghi\u00ean c\u1ee9u c\u1ee7a nh\u1eefng lo\u00e0i c\u00e2y tr\u1ed3ng. C\u00e1c t\u00e1c gi\u1ea3 c\u00f4ng tr\u00ecnh khoa h\u1ecdc n\u00e0y \u0111\u00e3 x\u00e1c \u0111\u1ecbnh \u0111\u01b0\u1ee3c h\u1ecd gen m\u00e3 h\u00f3a \u201cSUMO protease\u201d v\u00e0 ch\u1ee9ng minh \u0111\u01b0\u1ee3c vai tr\u00f2 c\u1ee7a OsOTS1 SUMO proteases khi c\u00e2y b\u1ecb stress do m\u1eb7n.<\/p>\n

Th\u1eadt th\u00fa v\u1ecb khi c\u00f3 hi\u1ec7n t\u01b0\u1ee3ng c\u00e2m gen trong c\u00e2y l\u00faa, OsOTS1 c\u00f2n cho th\u1ea5y l\u00e0m gi\u1ea3m \u0111\u00e1ng k\u1ec3 t\u1ef7 l\u1ec7 h\u1ea1t l\u00faa n\u1ea9y m\u1ea7m. Khi th\u1ef1c hi\u1ec7n k\u1ef9 thu\u1eadt knockdown gen OsOTS1, s\u1ef1 th\u1ec3 hi\u1ec7n gen n\u00e0y s\u1ebd \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn t\u0103ng tr\u01b0\u1edfng c\u1ee7a r\u1ec5 l\u00faa th\u00f4ng qua l\u00e0m gi\u1ea3m k\u00edch th\u01b0\u1edbc t\u1ebf b\u00e0o r\u1ec5 thay v\u00ec gia t\u0103ng s\u1ef1 ph\u00e2n b\u00e0o \u1edf r\u1ec5.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

M\u1eb7n l\u00e0 m\u1ed9t trong nh\u1eefng lo\u1ea1i h\u00ecnh g\u00e2y stress ch\u1ee7 y\u1ebfu trong m\u00f4i tr\u01b0\u1eddng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn n\u0103ng su\u1ea5t l\u00faa tr\u00ean to\u00e0n c\u1ea7u. C\u1ea3i ti\u1ebfn gi\u1ed1ng l\u00faa ch\u1ed1ng ch\u1ecbu m\u1eb7n l\u00e0 n\u1ed9i dung \u0111\u01b0\u1ee3c xem x\u00e9t c\u1ea5p thi\u1ebft ph\u1ee5c v\u1ee5 chi\u1ebfn l\u01b0\u1ee3c s\u1ea3n xu\u1ea5t l\u01b0\u01a1ng th\u1ef1c b\u1ec1n v\u1eefng.<\/p>\n","protected":false},"author":1,"featured_media":2786,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[87],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/posts\/6778"}],"collection":[{"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/comments?post=6778"}],"version-history":[{"count":0,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/posts\/6778\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/media\/2786"}],"wp:attachment":[{"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/media?parent=6778"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/categories?post=6778"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nbca.gov.vn\/wp-json\/wp\/v2\/tags?post=6778"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}