Thu\u1ed1c ph\u00f3ng x\u1ea1 F-18 FDG do Vi\u1ec7t Nam s\u1ea3n xu\u1ea5t \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong ghi h\u00ecnh PET\/CT, gi\u00fap ph\u00e1t hi\u1ec7n s\u1edbm trong ch\u1ea9n \u0111o\u00e1n, \u0111i\u1ec1u tr\u1ecb b\u1ec7nh ung th\u01b0.<\/p>\n

Trung t\u00e2m Chi\u1ebfu x\u1ea1 H\u00e0 N\u1ed9i thu\u1ed9c Vi\u1ec7n N\u0103ng l\u01b0\u1ee3ng nguy\u00ean t\u1eed Vi\u1ec7t Nam, B\u1ed9 Khoa h\u1ecdc v\u00e0 C\u00f4ng ngh\u1ec7, l\u00e0 c\u01a1 s\u1edf nghi\u00ean c\u1ee9u, \u1ee9ng d\u1ee5ng trong l\u0129nh v\u1ef1c n\u0103ng l\u01b0\u1ee3ng nguy\u00ean t\u1eed, v\u1edbi th\u1ebf m\u1ea1nh l\u00e0 c\u00e1c c\u00f4ng ngh\u1ec7 chi\u1ebfu x\u1ea1, b\u1ee9c x\u1ea1, h\u00f3a ph\u00f3ng x\u1ea1, gia t\u1ed1c v\u00e0 \u0111i\u1ec7n t\u1eed h\u1ea1t nh\u00e2n.<\/p>\n

\u0110\u00e2y l\u00e0 n\u01a1i \u0111\u1eb7t m\u00e1y gia t\u1ed1c cyclotron KOTRON 13MeV, d\u00f9ng \u0111\u1ec3 nghi\u00ean c\u1ee9u, s\u1ea3n xu\u1ea5t c\u00e1c \u0111\u1ed3ng v\u1ecb, d\u01b0\u1ee3c ch\u1ea5t ph\u00f3ng x\u1ea1. M\u00e1y gia t\u1ed1c n\u00e0y do Ch\u00ednh ph\u1ee7 H\u00e0n Qu\u1ed1c t\u1eb7ng Vi\u1ec7t Nam, B\u1ed9 Khoa h\u1ecdc v\u00e0 C\u00f4ng ngh\u1ec7 \u0111\u1ea1i di\u1ec7n ti\u1ebfp nh\u1eadn.<\/p>\n

T\u1eeb th\u00e1ng 2\/2023, sau nhi\u1ec1u n\u0103m xin c\u1ea5p ph\u00e9p, m\u00e1y gia t\u1ed1c b\u1eaft \u0111\u1ea7u \u0111\u01b0\u1ee3c Trung t\u00e2m s\u1eed d\u1ee5ng \u0111\u1ec3 s\u1ea3n xu\u1ea5t v\u00e0 cung c\u1ea5p thu\u1ed1c ph\u00f3ng x\u1ea1 F-18 FDG cho c\u00e1c b\u1ec7nh vi\u1ec7n. \u0110\u00e2y l\u00e0 lo\u1ea1i thu\u1ed1c ph\u00f3ng x\u1ea1 d\u00f9ng trong vi\u1ec7c ghi h\u00ecnh PET\/CT – ph\u01b0\u01a1ng ph\u00e1p ch\u1ea9n \u0111o\u00e1n h\u00ecnh \u1ea3nh k\u1ef9 thu\u1eadt cao \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh tim m\u1ea1ch, th\u1ea7n kinh v\u00e0 ung th\u01b0.<\/p>\n

T\u1eeb nguy\u00ean li\u1ec7u \u0111\u1ea7u v\u00e0o, sau kho\u1ea3ng th\u1eddi gian 2-2,5 gi\u1edd b\u1eafn ch\u00f9m proton v\u00e0o bia (ch\u1ee9a n\u01b0\u1edbc gi\u00e0u O-18), \u0111\u1ed3ng v\u1ecb O-18 s\u1ebd chuy\u1ec3n th\u00e0nh \u0111\u1ed3ng v\u1ecb F-18, v\u00e0 \u0111\u01b0\u1ee3c chuy\u1ec3n qua module t\u1ed5ng h\u1ee3p thu\u1ed1c. T\u1ea1i \u0111\u00e2y, trong qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p thu\u1ed1c ph\u00f3ng x\u1ea1, \u0111\u1ed3ng v\u1ecb F-18 s\u1ebd \u0111\u01b0\u1ee3c g\u1eafn v\u1edbi ti\u1ec1n ch\u1ea5t mannose triflate v\u00e0 th\u1ee7y ph\u00e2n \u0111\u1ec3 tr\u1edf th\u00e0nh d\u01b0\u1ee3c ch\u1ea5t ph\u00f3ng x\u1ea1 F-18 FDG. Trong \u1ea3nh l\u00e0 d\u01b0\u1ee3c ch\u1ea5t ph\u00f3ng x\u1ea1 F-18 FDG \u0111ang \u0111\u01b0\u1ee3c chia th\u00e0nh c\u00e1c li\u1ec1u nh\u1ecf sau qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p, tinh ch\u1ebf v\u00e0 l\u1ecdc v\u00f4 khu\u1ea9n.<\/p>\n

D\u01b0\u1ee3c ch\u1ea5t ph\u00f3ng x\u1ea1 F-18 FDG \u0111\u01b0\u1ee3c ti\u00eam v\u00e0o c\u01a1 th\u1ec3 ng\u01b0\u1eddi b\u1ec7nh theo \u0111\u01b0\u1eddng t\u0129nh m\u1ea1ch. F-18 FDG c\u00f3 th\u00e0nh ph\u1ea7n c\u1ea5u t\u1ea1o t\u01b0\u01a1ng t\u1ef1 \u0111\u01b0\u1eddng glucose. C\u00e1c t\u1ebf b\u00e0o ung th\u01b0 b\u1eaft glucose nhi\u1ec1u h\u01a1n nh\u1eefng t\u1ebf b\u00e0o b\u00ecnh th\u01b0\u1eddng. Khi v\u00e0o trong c\u01a1 th\u1ec3, F-18 FDG s\u1ebd h\u1ea5p th\u1ee5 nhi\u1ec1u v\u00e0o trong c\u00e1c t\u1ebf b\u00e0o ung th\u01b0, ph\u00e1t ph\u00f3ng x\u1ea1. M\u00e1y PET\/CT ghi l\u1ea1i qu\u00e1 tr\u00ecnh n\u00e0y, sau \u0111\u00f3 s\u1eed d\u1ee5ng m\u1ed9t ch\u01b0\u01a1ng tr\u00ecnh chuy\u1ec3n \u0111\u1ed5i th\u00e0nh h\u00ecnh \u1ea3nh, ph\u1ee5c v\u1ee5 cho vi\u1ec7c ch\u1ea9n \u0111o\u00e1n, \u0111i\u1ec1u tr\u1ecb b\u1ec7nh.<\/p>\n

L\u1ecd d\u01b0\u1ee3c ch\u1ea5t ph\u00f3ng x\u1ea1 F18-FDG sau khi s\u1ea3n xu\u1ea5t \u0111\u01b0\u1ee3c \u0111\u1eb7t v\u00e0o trong c\u00e1c container – m\u1ed9t h\u1ed9p nh\u1ecf l\u00e0m b\u1eb1ng vonfram v\u1edbi n\u1eafp kh\u00f3a \u0111\u1ec3 b\u1ea3o \u0111\u1ea3m an to\u00e0n ph\u00f3ng x\u1ea1 cho c\u00e1c nh\u00e2n vi\u00ean y t\u1ebf.<\/p>\n

T\u00f9y theo \u0111\u01a1n \u0111\u1eb7t h\u00e0ng, m\u1ed7i b\u1ec7nh vi\u1ec7n s\u1ebd nh\u1eadn v\u1ec1 t\u1eeb m\u1ed9t \u0111\u1ebfn hai container thu\u1ed1c ph\u00f3ng x\u1ea1. Hi\u1ec7n Trung t\u00e2m Chi\u1ebfu x\u1ea1 H\u00e0 N\u1ed9i \u0111ang cung c\u1ea5p thu\u1ed1c ph\u00f3ng x\u1ea1 cho 7 b\u1ec7nh vi\u1ec7n: B\u1ec7nh vi\u1ec7n K c\u01a1 s\u1edf T\u00e2n Tri\u1ec1u, B\u1ec7nh vi\u1ec7n Ung b\u01b0\u1edbu H\u00e0 N\u1ed9i, B\u1ec7nh vi\u1ec7n Qu\u00e2n \u0111\u1ed9i 103, B\u1ec7nh vi\u1ec7n \u0110\u1ea1i h\u1ecdc Phenikaa, B\u1ec7nh vi\u1ec7n \u0110a khoa Vinmec, B\u1ec7nh vi\u1ec7n M\u1eb7t tr\u1eddi v\u00e0 B\u1ec7nh vi\u1ec7n H\u00f2a B\u00ecnh \u1edf H\u1ea3i D\u01b0\u01a1ng.<\/p>\n

Nh\u00e2n vi\u00ean s\u1ea3n xu\u1ea5t \u0111\u1eb7t container v\u00e0o th\u00f9ng ch\u1ee9a ch\u1ed1ng s\u1ed1c \u0111\u1ec3 thu\u1ed1c kh\u00f4ng b\u1ecb x\u00f4 l\u1ec7ch, va \u0111\u1eadp trong qu\u00e1 tr\u00ecnh v\u1eadn chuy\u1ec3n. Container, th\u00f9ng ch\u1ee9a v\u00e0 ph\u01b0\u01a1ng ti\u1ec7n v\u1eadn chuy\u1ec3n thu\u1ed1c \u0111\u1ec1u ph\u1ea3i tu\u00e2n theo quy chu\u1ea9n v\u1ec1 an to\u00e0n b\u1ee9c x\u1ea1 h\u1ea1t nh\u00e2n.<\/p>\n

D\u01b0\u1ee3c ch\u1ea5t ph\u00f3ng x\u1ea1 F-18 FDG ph\u1ea3i tr\u1ea3i qua quy tr\u00ecnh ki\u1ec3m nghi\u1ec7m nghi\u00eam ng\u1eb7t tr\u01b0\u1edbc khi \u0111\u01b0\u1ee3c giao t\u1edbi c\u00e1c b\u1ec7nh vi\u1ec7n. \u0110\u00e2y l\u00e0 thu\u1ed1c ti\u00eam t\u0129nh m\u1ea1ch n\u00ean c\u00e1c ti\u00eau chu\u1ea9n ph\u1ea3i tu\u00e2n th\u1ee7 theo d\u01b0\u1ee3c \u0111i\u1ec3n.<\/p>\n

$\"\"$ Nh\u00e2n vi\u00ean ki\u1ec3m nghi\u1ec7m l\u1ea5y m\u1eabu thu\u1ed1c ph\u1ee5c v\u1ee5 vi\u1ec7c l\u01b0u th\u00e0nh ph\u1ea9m.<\/em><\/p>\n

M\u1ed9t ph\u1ea7n c\u1ee7a d\u01b0\u1ee3c ch\u1ea5t ph\u00f3ng x\u1ea1 F18-FDG l\u01b0u l\u1ea1i Trung t\u00e2m \u0111\u1ec3 ki\u1ec3m tra \u0111\u1ed1i ch\u1ee9ng.<\/em><\/p>\n<\/div>\n

\n
<\/p>\n
<\/p>\n
$\"\"$ <\/p>\n
S\u0129 quan an to\u00e0n \u0111o ch\u1ec9 s\u1ed1 ph\u00f3ng x\u1ea1 v\u1eadn chuy\u1ec3n c\u1ee7a container v\u00e0 ghi l\u00ean nh\u00e3n c\u1ea3nh b\u00e1o tr\u01b0\u1edbc khi d\u00e1n l\u00ean th\u00f9ng v\u1eadn chuy\u1ec3n, sau \u0111\u00f3 chuy\u1ec3n giao cho nh\u00e2n vi\u00ean y t\u1ebf.<\/p>\n
<\/p>\n
Th\u1eddi gian b\u00e1n r\u00e3 c\u1ee7a thu\u1ed1c ph\u00f3ng x\u1ea1 F-18 FDG l\u00e0 110 ph\u00fat (thu\u1ed1c ti\u00eau hao m\u1ea5t m\u1ed9t n\u1eeda sau m\u1ed7i 110 ph\u00fat), do v\u1eady vi\u1ec7c b\u00e0n giao, v\u1eadn chuy\u1ec3n thu\u1ed1c ph\u1ea3i di\u1ec5n ra nhanh ch\u00f3ng \u0111\u1ec3 tr\u00e1nh hao h\u1ee5t.<\/p>\n
<\/p>\n
\n
<\/p>\n
$\"\"$ <\/p>\n
Anh Nguy\u1ec5n Th\u1ebf Trung, nh\u00e2n vi\u00ean Khoa Y h\u1ecdc h\u1ea1t nh\u00e2n, B\u1ec7nh vi\u1ec7n K c\u01a1 s\u1edf T\u00e2n Tri\u1ec1u chuy\u1ec3n th\u00f9ng ch\u1ee9a thu\u1ed1c l\u00ean xe v\u1eadn chuy\u1ec3n chuy\u00ean d\u1ee5ng \u0111\u00e3 \u0111\u01b0\u1ee3c C\u1ee5c An to\u00e0n b\u1ee9c x\u1ea1 v\u00e0 h\u1ea1t nh\u00e2n c\u1ea5p ph\u00e9p.<\/p>\n
<\/p>\n
V\u1edbi m\u1ed9t m\u00e1y PET\/CT \u0111ang ho\u1ea1t \u0111\u1ed9ng, m\u1ed7i ng\u00e0y B\u1ec7nh vi\u1ec7n K c\u01a1 s\u1edf T\u00e2n Tri\u1ec1u hai l\u1ea7n \u0111\u1ebfn Trung t\u00e2m l\u1ea5y thu\u1ed1c \u0111\u1ec3 ph\u1ee5c v\u1ee5 cho kho\u1ea3ng 30 b\u1ec7nh nh\u00e2n. Theo anh Trung, ch\u1ec9 khi c\u00f3 thu\u1ed1c ph\u00f3ng x\u1ea1 F-18 FDG, c\u00e1c b\u00e1c s\u0129 m\u1edbi c\u00f3 th\u1ec3 ch\u1ee5p PET\/CT, t\u1eeb \u0111\u00f3 \u0111\u00e1nh gi\u00e1 \u0111\u00fang giai \u0111o\u1ea1n b\u1ec7nh tr\u01b0\u1edbc khi \u0111i\u1ec1u tr\u1ecb, x\u00e1c \u0111\u1ecbnh kh\u1ea3 n\u0103ng \u0111\u00e1p \u1ee9ng thu\u1ed1c v\u00e0 t\u00ecnh tr\u1ea1ng t\u00e1i ph\u00e1t, di c\u0103n c\u1ee7a b\u1ec7nh nh\u00e2n ung th\u01b0.<\/p>\n
<\/p>\n
T\u1ea1i Vi\u1ec7t Nam c\u00f3 Trung t\u00e2m Chi\u1ebfu x\u1ea1 H\u00e0 N\u1ed9i v\u00e0 m\u1ed9t s\u1ed1 b\u1ec7nh vi\u1ec7n s\u1eed d\u1ee5ng m\u00e1y gia t\u1ed1c ch\u1ee7 \u0111\u1ed9ng s\u1ea3n xu\u1ea5t d\u01b0\u1ee3c ch\u1ea5t ph\u00f3ng x\u1ea1 c\u00f3 th\u1eddi gian b\u00e1n r\u00e3 ng\u1eafn, ph\u1ee5c v\u1ee5 ch\u1ea9n \u0111o\u00e1n ung th\u01b0. Vi\u1ec7c ch\u1ee7 \u0111\u1ed9ng s\u1ea3n xu\u1ea5t thu\u1ed1c ph\u00f3ng x\u1ea1 F-18 FDG s\u1eed d\u1ee5ng trong ghi h\u00ecnh PET\/CT gi\u00fap ph\u00e1t hi\u1ec7n ung th\u01b0 s\u1edbm v\u00e0 mang l\u1ea1i hi\u1ec7u qu\u1ea3 cao trong ch\u1ea9n \u0111o\u00e1n, \u0111i\u1ec1u tr\u1ecb b\u1ec7nh.<\/p>\n<\/div>\n<\/div>\n
<\/p>\n
<\/p>\n
Ng\u1ecdc Th\u00e0nh – Tr\u1ecdng \u0110\u1ea1t<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"
Thu\u1ed1c ph\u00f3ng x\u1ea1 F-18 FDG do Vi\u1ec7t Nam s\u1ea3n xu\u1ea5t \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong ghi h\u00ecnh PET\/CT, gi\u00fap ph\u00e1t hi\u1ec7n s\u1edbm trong ch\u1ea9n \u0111o\u00e1n, \u0111i\u1ec1u tr\u1ecb b\u1ec7nh ung th\u01b0. Trung t\u00e2m Chi\u1ebfu x\u1ea1 H\u00e0 N\u1ed9i thu\u1ed9c Vi\u1ec7n N\u0103ng l\u01b0\u1ee3ng nguy\u00ean t\u1eed Vi\u1ec7t Nam, B\u1ed9 Khoa h\u1ecdc v\u00e0 C\u00f4ng ngh\u1ec7, l\u00e0 c\u01a1 s\u1edf […]<\/p>\n","protected":false},"author":4,"featured_media":18927,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[26],"tags":[],"class_list":["post-18914","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tong-hop"],"_links":{"self":[{"href":"https:\/\/vinatom.gov.vn\/wp-json\/wp\/v2\/posts\/18914","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vinatom.gov.vn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vinatom.gov.vn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vinatom.gov.vn\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/vinatom.gov.vn\/wp-json\/wp\/v2\/comments?post=18914"}],"version-history":[{"count":1,"href":"https:\/\/vinatom.gov.vn\/wp-json\/wp\/v2\/posts\/18914\/revisions"}],"predecessor-version":[{"id":18928,"href":"https:\/\/vinatom.gov.vn\/wp-json\/wp\/v2\/posts\/18914\/revisions\/18928"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vinatom.gov.vn\/wp-json\/wp\/v2\/media\/18927"}],"wp:attachment":[{"href":"https:\/\/vinatom.gov.vn\/wp-json\/wp\/v2\/media?parent=18914"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vinatom.gov.vn\/wp-json\/wp\/v2\/categories?post=18914"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vinatom.gov.vn\/wp-json\/wp\/v2\/tags?post=18914"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}